American Board of Psychiatry and Neurology (ABPN) Practice Exam 2026 - Free ABPN Practice Questions and Study Guide

Question: 1 / 1275

Which medication is contraindicated before electroconvulsive therapy because it can prolong seizure activity?

Lithium

Lithium is contraindicated before electroconvulsive therapy (ECT) primarily because it has been associated with an increased risk of prolonged seizure activity. ECT induces controlled seizures in the brain as part of its therapeutic mechanism, and lithium, when present in the body, can potentially exacerbate or prolong these seizures. This effect can be particularly concerning, as prolonged seizures may lead to complications, such as postictal confusion or even physical injury due to the intensity and duration of the seizure.

In contrast, while olanzapine, selegiline, and thioridazine might have other interactions or side effects related to ECT, they do not carry the same risk of significantly prolonging seizure activity. Therefore, managing the medication regimen carefully in advance of ECT is crucial, particularly regarding lithium use, to ensure patient safety and the efficacy of the ECT treatment.

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Olanzapine

Selegiline

Thioridazine

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